Biological Information
Background Information:
Müllerian inhibiting substance (MIS), also known as anti-Müllerian hormone (AMH), is a tissue-specific TGF-β superfamily growth factor. MIS is synthesized and secreted as a 553 aa disulfide-linked homodimeric pro-protein. Proteolytic cleavage generates an N-terminal pro-region and the C-terminal bioactive protein, which remain associated in a non-covalent complex. Recombinant C-terminal MIS has been shown to be bioactive. MIS has been shown to regulate gonadal functions, inhibit Leydig cell proliferation and is a regulator of the initial and cyclic recruitment of ovarian follicles.
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®