MKK6/SKK3, unactive

Background Information:

MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) Kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. EMBL U39657

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MKK6

Protein Aliases:

protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)

Accession Number:

NM_002758.3

UniProt Number:

P52564

Gene Name:

MAP2K6

Gene ID:

5608

Gene Aliases:

MEK6|MKK6|SAPKK3|MAPKK6|PRKMK6|SKK3

Target Species:

Human