MEKK2, active

Background Information:

MEKK2 is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. GenBank NM_006609.3

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MEKK2

Protein Aliases:

MAP/ERK kinase kinase 2

Accession Number:

NM_006609.3

UniProt Number:

Q9Y2U5

Gene Name:

MAP3K2

Gene ID:

10746

Gene Aliases:

MEKK2B|MAPKKK2|MEKK2

Target Species:

Human