Biological Information

Background Information:

The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for JAK1. All reagents are provided in the kit, including recombinant JAK1 (Eurofins #14-918), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for twenty five 384-well assay plates.

Target Class:

Kinase

Family:

TK

Sub Family:

Serine/threonine kinase

Protein Name:

JAK1

Protein Aliases:

JAK-1

Accession Number:

NM_002227.1

UniProt Number:

P23458

Gene Name:

JAK1

Gene ID:

3716

Gene Aliases:

JAK1A|JTK3

Target Species:

Human

Usage

Product Type:

Enzyme Activity Assay Kits

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Measures:

ADP Accumulation

Detection Method:

Fluorescence

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy/Oncology/Immuno-Oncology

Additional Information

Brand: