Biological Information

Background Information:

GRK1 is a retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

GRK1

Protein Aliases:

G protein-coupled receptor kinase 7|G protein-coupled receptor kinase GRK7

Accession Number:

NP_002920

UniProt Number:

Q15835

Gene Name:

GRK1

Gene ID:

6011

Gene Aliases:

GPRK1|RK|RHOK

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only