Biological Information

Background Information:

N-terminal GST-tagged, recombinant, human EphA6, amino acids 683-end. EphA6 is a receptor tyrosine kinase which binds ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. It plays a key role in axon guidance and nervous system development and is also being investigated as a potential therapeutic target due its overexpression in prostate and breast cancer.

Target Class:

Kinase

Family:

Eph receptor

Sub Family:

Tyrosine kinase

Protein Name:

EphA6

Protein Aliases:

EHK-2; EK12

Accession Number:

NM_001080448.3

UniProt Number:

Q9UF33

Gene Name:

EPHA6

Gene ID:

285220

Gene Aliases:

EHK2; EK12; EPA6; EHK-2; HEK12; PRO57066

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology