Biological Information
Background Information:
Embelin is a natural cell-permeable benzoquinone inhibitor of the X-linked inhibitor of apoptosis (XIAP) protein (IC50=4.1uM), acting as an anti-tumor, anti-inflammatory, and analgesic. Activates caspases, blocks growth, and promotes apoptosis in tumor cells with high levels of XIAP. Also prevents XIAP- and caspase-dependent inflammation, and inhibits IKK, preventing NF-kB activation. Also acts as an agonist for GPR84. Provided as 10 mg of dry powder.
Usage
Product Type:
Control Ligands & Inhibitors
Application:
Drug Discovery & Development
Storage Conditions:
Store at 2-8°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®