Biological Information

Background Information:

The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for DYRK1B. All reagents are provided in the kit, including recombinant DYRK1B (Eurofins #14-944), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for two, six or twenty five 384-well assay plates.

Target Class:

Kinase

Family:

CMGC

Sub Family:

Serine/threonine/tyrosine kinase

Protein Name:

DYRK1B

Protein Aliases:

MIRK

Accession Number:

NM_004714.1

UniProt Number:

Q9Y463

Gene Name:

DYRK1B

Gene ID:

9149

Gene Aliases:

MIRK; AOMS3

Target Species:

Human

Usage

Product Type:

Enzyme Activity Assay Kits

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Assay Measures:

ADP Accumulation

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Metabolic Diseases/Oncology