Biological Information

Background Information:

Myotonic dystrophy (DM1) is the most common form of muscular dystrophy in adults, caused by amplification of an unstable (CTG)n repeat in the 3' untranslated region (3'-UTR) of the DM1 protein kinase (DMPK) gene. Myotonic dystrophy protein kinase (DMPK) is a serine threonine kinase encoded by the DM-1 locus. GenBank NM_004409

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

DMPK

Protein Aliases:

dystrophia myotonica 1|DM protein kinase|myotonin protein kinase A|myotonic dystrophy associated protein kinase|thymopoietin homolog

Accession Number:

NM_001081560.1; NM_001081562.1; NM_001081563.1; NM_004409.3

UniProt Number:

Q09013

Gene Name:

DMPK

Gene ID:

1760

Gene Aliases:

DMK|DM1PK|MDPK|MT-PK

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology