DDX3Y, active

Background Information:

DDX3Y is an ATP-dependent RNA helicase involved in various aspects of RNA metabolism, including translation initiation and RNA splicing. It plays a crucial role in spermatogenesis and is expressed predominantly in male germ cells. Mutations in DDX3Y are linked to male infertility, particularly Sertoli cell-only syndrome. It may also have implications in immune response modulation and could be a target in male-specific cancers or fertility treatments.

Target Class:

Helicase

Family:

DEAD-box

Sub Family:

RNA helicase

Protein Name:

DDX3Y

Protein Aliases:

DBY

Accession Number:

NM_001122665.3

UniProt Number:

O15523

Gene Name:

DDX3Y

Gene ID:

8653

Gene Aliases:

DBY

Target Species:

Human