Biological Information

Background Information:

Members of the cyclin-dependent kinase pair CDK9/cyclinT1, also called positive transcription elongation factor b (P-TEFb), facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. GenBank AF517840 / GenBank NM_001240

Target Class:

Kinase

Family:

CMGC

Sub Family:

Protein Ser/Thr

Protein Name:

CDK9

Protein Aliases:

|C-2K|Cell division cycle 2-like protein kinase 4|Cell division protein kinase 9|Serine/threonine-protein kinase PITALRE|Tat-associated kinase complex catalytic subunit

Accession Number:

NM_001261.2

UniProt Number:

P50750

Gene Name:

CDK9

Gene ID:

1025

Gene Aliases:

PITALRE|C-2k|TAK

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology