Biological Information

Background Information:

CaM Kinase Iδ Protein is a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. May be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1. GenBank NM_153498

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

CaMK1delta

Protein Aliases:

CaM kinase I delta|CaM kinase ID|CaM-KI delta|CaMKI delta|CaMKID|CaMKI-like protein kinase|CKLiK

Accession Number:

NM_020397.2; NM_153498.2

UniProt Number:

Q8IU85

Gene Name:

CAMK1D

Gene ID:

57118

Gene Aliases:

CKLiK|CAMKID

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology