Biological Information

Background Information:

MAP4K3 is a member of the mitogen-activated protein Kinase kinase family. The encoded protein activates key effectors in cell Signaling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. Among its related pathways are TGF-Beta Pathway and Angiopoietin-like protein 8 regulatory pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K5.[provided by RefSeq, Jul 2012]

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MAP4K3

Protein Aliases:

Germinal center kinase-related protein kinase|GLK|MAPK/ERK kinase kinase kinase 3|MEK kinase kinase 3|MEKKK 3

Accession Number:

NM_003618.2

UniProt Number:

Q8IVH8

Gene Name:

MAP4K3

Gene ID:

8491

Gene Aliases:

GLK|MAPKKKK3|MAP4K3|RAB8IPL1

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only