Biological Information
Background Information:
MAP4K3 is a member of the mitogen-activated protein Kinase kinase family. The encoded protein activates key effectors in cell Signaling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. Among its related pathways are TGF-Beta Pathway and Angiopoietin-like protein 8 regulatory pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K5.[provided by RefSeq, Jul 2012]
Target Class:
Kinase
Family:
STE
Sub Family:
Protein Ser/Thr
Protein Name:
MAP4K3
Protein Aliases:
Germinal center kinase-related protein kinase|GLK|MAPK/ERK kinase kinase kinase 3|MEK kinase kinase 3|MEKKK 3
Accession Number:
NM_003618.2
UniProt Number:
Q8IVH8
Gene Name:
MAP4K3
Gene ID:
8491
Gene Aliases:
GLK|MAPKKKK3|MAP4K3|RAB8IPL1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only