Biological Information

Background Information:

FTY 720 phosphate, or Fingolimod, is a sphingosine analog and immunomodulating drug currently approved for multiple sclerosis treatment. It is derived from the fungal metabolite myriocin (ISP-1), and acts as a potent modulator for sphingosine-1 phosphate receptors, encouraging recruitment of lymphocytes into the CNS during an immune response. Acts as an agonist for S1P1 receptors S1PR1 (EDG1) and S1PR5 (EDG8) selectively, with no activity at S1PR2-4. Provided as 1 mg of dry powder.

Usage

Product Type:

Control Ligands & Inhibitors

Application:

Drug Discovery & Development

Storage Conditions:

Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Additional Information

Brand:

Eurofins DiscoverX®