ChemiSCREEN™ M3 Muscarinic Acetylcholine Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ M3 Muscarinic Acetylcholine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CHRM3 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Acetylcholine (Muscarinic)

Sub Family:

Class A

Protein Name:

M3

Protein Aliases:

acetylcholine receptor, muscarinic 3

Accession Number:

NM_000740

UniProt Number:

P20309

Gene Name:

CHRM3

Gene ID:

1131

Target Species:

Human

Cell Background:

Chem-1