ChemiSCREEN™ CCR8 Chemokine Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ CCR8 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCR8 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Chemokine

Sub Family:

Class A

Protein Name:

CCR8

Protein Aliases:

CC-CKR-8|CCR-8|CC chemokine receptor CHEMR1|CMKBRL2|Chemokine receptor-like 1|CKR-L1|GPR-CY6|GPRCY6|TER1|CD antigen CDw198

Accession Number:

U45983

UniProt Number:

P51685

Gene Name:

CCR8

Gene ID:

1237

Gene Aliases:

CY6|TER1|CKR-L1|GPR-CY6|CDw198

Target Species:

Human

Cell Background:

Chem-1