ChemiSCREEN™ CB1 Cannabinoid Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ CB1 Cannabinoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CNR1 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Cannabinoid

Sub Family:

Class A

Protein Name:

CB1

Protein Aliases:

CB1|CANN6

Accession Number:

AY225225

UniProt Number:

P21554

Gene Name:

CNR1

Gene ID:

1268

Gene Aliases:

CB1K5|CB-R|CB1|CANN6|CB1A

Target Species:

Human

Cell Background:

Chem-1